An Arms Race Against Evolution: Why the Mathematics of Antibiotic Resistance May Determine Medicine's Future
Antibiotic-resistant bacteria kill tens of thousands of Americans each year, and that number is rising. The mathematical tools needed to understand and potentially outmaneuver bacterial evolution — differential equations, population dynamics, game theory — exist and are being applied. But a persistent gap between the laboratory of the applied mathematician and the reality of the clinic is undermining progress at precisely the moment it is most needed.